
PHA767491 HCl
CAS No. 942425-68-5
PHA767491 HCl( CAY-10572 hydrochloride )
Catalog No. M19277 CAS No. 942425-68-5
PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 39 | Get Quote |
![]() ![]() |
10MG | 55 | Get Quote |
![]() ![]() |
25MG | 88 | Get Quote |
![]() ![]() |
50MG | 129 | Get Quote |
![]() ![]() |
100MG | 212 | Get Quote |
![]() ![]() |
200MG | 313 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NamePHA767491 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionPHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM).
-
DescriptionPHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
-
In Vitro——
-
In Vivo——
-
SynonymsCAY-10572 hydrochloride
-
PathwayEndocrinology/Hormones
-
TargetReductase
-
RecptorCdk1| Cdk2| Cdk9| Cdc7| GSK-3β
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number942425-68-5
-
Formula Weight213.24
-
Molecular FormulaC12H11N3O
-
Purity>98% (HPLC)
-
SolubilityDMSO : 17.33 mg/mL 69.40 mM
-
SMILESCl.O=C1NCCc2nc(cc12)c3ccncc3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Montagnoli A, et al. Nat Chem Biol, 2008, 4(6), 357-365.
molnova catalog



related products
-
Lidorestat
Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity. Lidorestat improves nerve conduction and reduces the formation of cataracts.
-
12-O-Methylcarnosic ...
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.12-O-Methylcarnosic acid has antioxidant activity, it is effective preventing gastric lesions.?
-
Minalrestat
Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients.